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Home You Want To Know Everything you need to know about upper GI Endoscopy.

Everything you need to know about upper GI Endoscopy.

Endoscopy allows doctors to see exactly what is going on inside the GI tract, helping determine an accurate course of treatment.
Endoscopy allows doctors to see exactly what is going on inside the GI tract, helping determine an accurate course of treatment.

If you present symptoms of Celiac disease and your blood tests come back positive, your doctor may order an “Upper Gl” or an upper gastrointestinal endoscopy to examine the lining of your small intestine. Here’s everything you need to know, courtesy of, and shared with permission from, the National Institutes of Health. 

What is upper gastrointestinal (GI) endoscopy?

Upper Gl endoscopy is a procedure in which a doctor uses an endoscope-a long, flexible tube with a camera to see the lining of your upper GI tract. A gastroenterologist, surgeon, or other trained health care provider performs the procedure, most often while you receive light sedation. Your doctor may also call the procedure an EGD or esophagogastroduodenoscopy. 

Why do doctors use upper GI endoscopy?

Endoscopy allows the doctor a close-up view of one’s gastrointestinal tract.

Upper Gl endoscopy can help find the cause of unexplained symptoms, such as: 

  • persistent heartburn 
  • bleeding 
  • nausea and vomiting
  • pain 
  • problems swallowing 
  • unexplained weight loss 
Upper Gl endoscopy can also find the cause of abnormal lab tests, such as: 
  • anemia 
  • nutritional deficiencies 
Upper Gl endoscopy can identify many different diseases: 
  • anemia 
  • gastro-esophageal reflux disease 
  • ulcers 
  • cancer 
  • inflammation, or swelling 
  • precancerous abnormalities 
  • celiac disease 


During upper Gl endoscopy, a doctor obtains biopsies by passing an instrument through the endoscope to obtain a small piece of tissue. Biopsies are needed to diagnose conditions such as: 

  • cancer 
  • celiac disease 
  • gastritis 



During an endoscopy, doctors can take a tissue sample of the intestinal lining.
During an endoscopy, doctors can take a tissue sample of the intestinal lining.

Doctors also use upper Gl endoscopy to: 

  • treat conditions such as bleeding ulcers  
  • dilate strictures with a small balloon passed through the endoscope 
  • remove objects, including food, that may be stuck in the upper GI tract 
How do I prepare for an upper GI endoscopy?

Talk with your doctor about all medical conditions you have and all prescribed and over-the-counter medicines, vitamins, and supplements you take, including 

  • aspirin or medicines that contain aspirin 
  • arthritis medicines. non steroidal anti-inflammatory drugs such as ibuprofen and naproxen
  • blood thinners 
  • blood pressure medicines 
  • diabetes medicines 

Arrange for a ride home

For safety reasons, you can’t drive for 24 hours after the procedure, as the sedatives used during the procedure need time to wear off. You will need to make plans for getting a ride home after the procedure. 


An endoscope is inserted through the mouth into the GI tract so that the intestine can be viewed via a tiny camera. 

Do not eat or drink before the procedure 

The doctor needs to examine the lining of your upper GI tract during the procedure. If food or drink is in your upper GI tract when you have the procedure, the doctor will not be able to see this lining clearly. To make sure your upper GI tract is clear, the doctor will most often advise you not to eat, drink, smoke, or chew gum during the 8 hours before the procedure. 


How do doctors perform an upper Gl endoscopy?

 A doctor performs an upper Gl endoscopy in a hospital or an outpatient center. An intravenous (IV) needle will be placed in your arm to provide a sedative. Sedatives help you stay relaxed and comfortable during the procedure. In some cases, the procedure can be performed without sedation. You will be given a liquid anesthetic to gargle or spray anesthetic on the back of your throat. The anesthetic numbs your throat and calms the gag reflex. The health care staff will monitor your vital signs and keep you as comfortable as possible. 

You’ll be asked to lie on your side on an exam table. The doctor will carefully feed the endoscope down your esophagus and into your stomach and duodenum. A small camera mounted on the endoscope will send a video image to a monitor, allowing close examination of the lining of your upper GI tract. The endoscope pumps air into your stomach and duodenum, making them easier to see. 

During the upper Gl endoscopy, the doctor may:


  • perform a biopsy of tissue in your upper GI tract. You won’t feel the biopsy. 
  • stop any bleeding.
  • perform other specialized procedures, such as dilating strictures.

What should I expect from an upper GI endoscopy?

 After an upper Gl endoscopy, you can expect the following: 

  • to stay at the hospital or outpatient center for 1 to 2 hours after the procedure so the sedative can wear off 
  • bloating or nausea for a short time after the procedure 
  • a sore throat for 1 to 2 days to go back to your normal diet once your swallowing has returned to normal 
  • to rest at home for the remainder of the day 

Following the procedure, you or a friend or family member who is with you if you’re still groggy–will receive instructions on how to care for yourself following the procedure. You should follow all the instructions. Some results from an upper Gl endoscopy are available right away after the procedure. After the sedative has worn off, the doctor will share these results with you or, if you choose, with your friend or family member. A pathologist will examine the biopsy tissue to help confirm a diagnosis. Biopsy results take a few days or longer to come back. 

What are the risks of an upper GI endoscopy?

The risks of an upper GI endoscopy include: 

  • bleeding from the site where the doctor took the biopsy or removed a polyp 
  • perforation in the lining of your upper Gl tract 
  • an abnormal reaction to the sedative, including respiratory or cardiac problems.

Bleeding and perforation are more common in endoscopies used for treatment rather than testing. Bleeding caused by the procedure often stops without treatment. Research has shown that serious complications occur in one out of every 1,000 upper Gl endoscopies. A doctor may need to perform surgery to treat some complications. A doctor can treat an abnormal reaction to a sedative with medicines or IV fluids during or after the procedure.

Seek medical care right away if you have any of the following symptoms after an upper Gl endoscopy: 
  • chest pain 
  • problems breathing 
  • problems swallowing or throat pain that gets worse 
  • vomiting-particularly if your vomit is bloody or looks like coffee grounds 
  • pain in your abdomen that gets worse 
  • bloody or black, tar-colored stool 
  • fever 

REFERENCES: 1Yusuf TE, Bhutani MS. Esophagogastroduodenoscopy. Medscape website. http://emedicine.medscape. com/article/1851864-overview #a17. Updated June 3, 2013. Accessed July 8, 2014. 



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